Solid-Phase Synthesis of Peptides with Bulky Dehydroamino Acids ID: 2014-105
A novel method for efficiently incorporating bulky dehydroamino acids into peptides, enhancing their stability and target binding.
Photo by starlineart - stock.adobe.com
Technology Overview
This technology presents a solid-phase synthesis approach for creating peptides that include bulky dehydroamino acids. By preparing azlactone dipeptides and utilizing resin-bound peptides for ring-opening reactions, this method overcomes previous challenges in peptide synthesis, offering a more streamlined process. This advancement not only improves peptide stability and binding affinity to biological targets but also opens new avenues in therapeutic peptide development.
Key Advantages
- Enhanced peptide stability
- Improved binding to biological targets
- Streamlined synthesis process
- Overcomes limitations of solution-phase synthesis
- Facilitates the incorporation of bulky amino acids into peptides
Problems Addressed
- Difficulty in incorporating bulky dehydroamino acids into peptides
- Time-consuming solution-phase synthesis methods
- Limited stability and binding efficiency of therapeutic peptides
Market Applications
- Pharmaceutical development of peptide-based drugs
- Biotechnology research and development
- Therapeutic peptide design and synthesis
- Drug stability and efficacy improvement
Additional Information
Technology ID: 2014-105
Sell Sheet: Download the Sell Sheet here
Market Analysis: Contact us for a more in-depth market report
Date Published: 07 May, 2025
Connect with the Tech Transfer to:
- Meet with the technology manager
- Receive additional information
- Request a marketing plan report