Short Column Gas Chromatography ID: 2013-059

A novel method and apparatus for enhancing the separation of analytes in gas chromatography using short columns.

Technology Overview

This technology, developed by H. Dennis Tolley and Samuel E. Tolley, introduces an innovative approach to gas chromatography (GC) by utilizing short columns and a moving thermal gradient to improve the separation efficiency of volatile and semi-volatile analytes. This method is designed to overcome the limitations of traditional GC by offering high resolution and narrow peak widths, even with shorter column lengths.

Key Advantages

• Enhanced separation efficiency through a moving thermal gradient
• High resolution and narrow peak widths with short column lengths
• Increased flexibility and efficiency by adjusting thermal gradients and mobile phase velocity
• Compatibility with portable GC systems and "lab on a chip" applications
• Optimized separation parameters via an included feedback mechanism

Problems Addressed

• Limitations of traditional gas chromatography in separation efficiency
• Challenges in achieving high resolution with short columns
• Constraints of power and back pressure in compact and resource-limited settings
• Imperfect injections and band broadening issues

Market Applications

• Portable gas chromatography systems for field and workplace monitoring
• Compact "lab on a chip" applications for on-the-go analysis
• Environmental monitoring where power and space are limited
• Quality control in various industries requiring efficient analyte separation

Additional Information

Technology ID: 2013-059
Sell Sheet: Download the Sell Sheet here
Market Analysis: Contact us for a more in-depth market report
Date Published: 13 May, 2025