Scaphopetalone Analogs for Antiviral Therapy ID: 2015-057
A breakthrough in antiviral therapy targeting herpes viruses through the development of scaphopetalone analogs.

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Technology Overview
The document details the research and development of scaphopetalone analogs, derived from Kalanchoe pinnata, focusing on their synthesis, chemical structures, and antiviral properties against herpes viruses. These compounds, notably F4-0 and F4-4, are demonstrated to inhibit Herpes simplex viruses 1 and 2 as well as Herpes zostera, offering a new approach to treating viral infections such as cold sores, genital herpes, and shingles.
Key Advantages
- Derived from Kalanchoe pinnata, a plant known for its medicinal properties
- Effective against both Herpes simplex virus types 1 and 2, and Herpes zostera
- Utilizes innovative chemical synthesis methods, including intramolecular Diels-Alder reactions
- Capable of inhibiting viral DNA synthesis, reducing disease manifestations
Problems Addressed
- Addresses the need for more effective antiviral therapies against herpes viruses
- Overcomes limitations of current treatments that may not target all herpes virus types effectively
- Provides a potential solution to reduce the global burden of conditions caused by herpes viruses, including cold sores, genital herpes, and shingles
Market Applications
- Pharmaceutical development for antiviral drugs
- Therapeutic treatments for viral infections, specifically herpes-related conditions
- Research and development in medicinal chemistry focusing on plant-derived compounds
Additional Information
Technology ID: 2015-057
Sell Sheet: Download the Sell Sheet here
Market Analysis: Contact us for a more in-depth market report
Date Published: 28 March, 2025
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