Pseudo-Bistable, Pseudo-Rigid Compliant Heart Valve Replacement ID: 2014-055

A revolutionary heart valve design that mimics the natural aortic valve to improve patient outcomes and reduce common complications.

Technology Overview

This innovative heart valve replacement design from Brigham Young University aims to closely replicate the function of a healthy aortic valve. It addresses the limitations of current bioprosthetic and mechanical valves by minimizing blood flow disruption, hemolysis, clotting, ossification, mechanical fatigue, and immunologic rejection. The stentless, foldable design facilitates potential percutaneous delivery. It features three independently operating flaps connected by living hinges for a pseudo-rigid functionality, maximizing blood flow efficiency.

Key Advantages

• Stentless and foldable design allows for less invasive percutaneous delivery
• Three-flap mechanism operates independently to closely mimic natural heart valve dynamics
• Maximizes geometric orifice area, significantly improving blood flow compared to existing mechanical valves
• Material choice of PTFE with or without PDMS coating reduces risks of coagulation and ossification
• Addresses common issues with existing valve replacements such as hemolysis, clotting, and immunologic rejection

Problems Addressed

• Blood flow disruption common in current valve replacement technologies
• Increased risk of hemolysis and clotting in patients with existing mechanical or bioprosthetic valves
• Ossification and mechanical fatigue leading to the need for repeated surgeries
• Immunologic rejection faced by patients with bioprosthetic valves

Market Applications

• Replacement for diseased or malfunctioning aortic valves
• Alternative to bioprosthetic and mechanical heart valves for patients requiring valve replacement surgery
• Potential use in minimally invasive cardiac surgery techniques
• Application in developing next-generation heart valves with improved longevity and patient compatibility

Additional Information

Technology ID: 2014-055
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Date Published: 06 May, 2025