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Positively Charged Reversed-Phase Chromatographic Media ID: 2012-063

A novel chromatographic media that combines hydrophobic and ionic characteristics for enhanced mixed-mode separations.

2012-063 photo
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Technology Overview

This technology introduces a new stationary phase material for liquid chromatography features both reversed-phase (hydrophobic) and positively charged (ionic) properties. By undergoing a two-step synthesis process involving the functionalization of a porous metal oxide substrate with amino groups and the subsequent attachment of hydrophobic alkyl chains, this material achieves unique chromatographic selectivity, enabling the effective separation of complex mixtures, particularly acidic compounds.


Key Advantages

  • Combines hydrophobic and ionic interactions, offering mixed-mode separations
  • Provides superior separation of acidic compounds compared to commercially available media
  • Exhibits long-term stability and robustness with over 200 injections
  • Unique positive charge mechanism enhances selectivity and performance

Problems Addressed

  • Improves the separation of acidic compounds, including herbicides, that are challenging for standard media
  • Overcomes limitations of commercial chromatographic media with enhanced selectivity and stability

Market Applications

  • Pharmaceutical analysis and purification
  • Environmental monitoring and testing for herbicides and other acidic pollutants
  • Chemical and biochemical research requiring precise separation capabilities
  • Potential licensing opportunities with companies specializing in chromatographic technologies, such as US Synthetic

Additional Information

Technology ID: 2012-063
Sell Sheet: Download the Sell Sheet here
Market Analysis: Contact us for a more in-depth market report
Date Published: 30 June, 2025

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