Non-Invasive Diagnostic Tool for Coronary Artery Disease Using DNA Methylation Signatures ID: 2023-005
A groundbreaking diagnostic approach for coronary artery disease, leveraging blood plasma-derived DNA methylation signatures for pre-symptomatic detection.
Technology Overview:
This innovative technology offers a minimally invasive diagnostic solution for coronary artery disease by analyzing cell-free DNA in blood plasma to identify unique methylation patterns indicative of the disease. Utilizing a two-step process involving amplification and sequencing of blood-derived DNA, followed by analysis through a specialized Python-based pipeline, this tool can accurately detect coronary artery disease before symptoms arise.
Key Advantages
- Significantly reduces healthcare costs by offering a less expensive diagnostic alternative.
- Increases diagnostic accuracy through the use of stable biomarkers.
- Improves patient experience by eliminating the need for invasive procedures such as coronary angiograms.
- Facilitates integration into regular medical screenings, streamlining the diagnostic process.
Problems Solved
- Reduces reliance on costly, inferential, and invasive diagnostic practices.
- Offers a pre-symptomatic diagnosis, potentially improving treatment outcomes and patient prognosis.
Market Applications
- Use in hospitals and clinics as part of regular health screenings to identify at-risk individuals early.
- Integration into existing diagnostic workflows to provide a comprehensive cardiovascular health assessment.
- Potential licensing opportunities to laboratories and corporations for broader commercialization.
Stage of Development
The technology is in the prototype stage. Initial prototypes have been developed to demonstrate its functionality, but further testing and refinement are needed before it can be considered for commercial deployment.
Additional Information
Technology ID: 2023-005
Sell Sheet: Download the Sell Sheet here
Marketing Analysis: Link to Market Analysis here
Date Published: March 18, 2025
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