Gradient-Delay Multiplexed Liquid Chromatography ID: 2018-060
A novel liquid chromatography method that enhances throughput and reduces costs by optimizing mass spectrometer duty cycles.
Photo by MORENO SOPPELSA
Technology Overview
This technological innovation introduces a method for rapid liquid chromatography separations by utilizing a single binary gradient liquid chromatography pumping system. It splits the mobile phase among multiple LC columns, enabling staggered analysis times with a single pump. This approach not only improves throughput but also significantly lowers operational costs by reducing the need for multiple systems.
Key Advantages
- Significantly improves throughput with staggered analysis times
- Reduces operational costs by utilizing a single pump for multiple LC columns
- Maximizes detector productivity, especially beneficial for high-throughput proteomic analyses
- Enables simultaneous purging, regeneration, sample loading, and injection across multiple columns
Problems Addressed
- High costs associated with commercial liquid chromatography systems requiring multiple pumps
- Low throughput and efficiency in proteomic analyses due to limitations in existing LC separation technologies
- Challenges in achieving high resolution and throughput in single-cell proteomic analyses
Market Applications
- High-throughput proteomic analysis in research and clinical laboratories
- Cost-effective chemical analysis for pharmaceutical and biotechnological industries
- Advanced analytical tools for cancer research funded by NIH National Cancer Institute and other healthcare research initiatives
Additional Information
Technology ID: 2018-060
Sell Sheet: Download the Sell Sheet here
Market Analysis: Contact us for a more in-depth market report
Date Published: 28 March, 2025
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