3D Cones MRI Technology for Tauopathy Detection ID: 2014-017

An innovative application of 3D Cones MRI technology to detect tauopathy in brains by identifying protein-bound water.

Technology Overview

This technology utilizes the advanced capabilities of 3D Cones MRI to indirectly measure the deposition of tau proteins in the brain, a key indicator of Alzheimer's disease and other tauopathies, by observing changes in MRI relaxation properties related to protein-bound water. Developed by Brigham Young University, it addresses the critical gap in existing MRI methods for imaging proteins within the brain.

Key Advantages

• Enables the detection of tau proteins, crucial for diagnosing Alzheimer's disease and other tauopathies
• Provides a non-invasive method for assessing protein deposition in the brain
• Offers a significant improvement over existing MRI techniques which lack the ability to image brain proteins directly
• Potentially increases the accuracy and early detection of tauopathies

Problems Addressed

• Lack of effective MRI methods to image proteins in the brain
• Difficulties in the early and accurate diagnosis of Alzheimer's disease and other tauopathies

Market Applications

• Diagnostic tool for neuroradiologists to assess tau protein deposition in patients
• Research tool in clinical studies focusing on Alzheimer's disease and tauopathy
• Potential for collaboration with MRI equipment manufacturers, such as Siemens USA, for technology licensing

Additional Information

Technology ID: 2014-017
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Date Published: 06 May, 2025